(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate → HCID 86661985, Verbindung
Reaktionsgleichung
[N:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[O:16]1[CH2:18][CH:17]1[CH2:19]OS(C1C=CC=C([N+]([O-])=O)C=1)(=O)=O>>[O:16]1[CH2:18][CH:17]1[CH2:19][N:13]1[CH2:12][CH2:11][N:10]([CH2:9][CH2:8][CH2:7][N:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)[CH2:15][CH2:14]1Komponenten
3
Versuchsvorschrift
The same method as employed in the preparation of Intermediate 1 but starting from 1-(3-piperidin-1-ylpropyl)piperazine and (±)-3-nitro-benzenesulfonic acid oxiranylmethyl ester gives after flash chromatography the title compound as an orange oil in a 64% yield.
Quellen und Nachweise
- ORD-Eintrag
- ord-e43035e4d861400b8323908fd3b8502c
- Quelldatensatz
- uspto-grants-2013_04