HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
p-Formylphenylboric acid → 2-(Trimethylsilyl)ethyl 4-(4-formylphenyl)isoquinoline-6-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | p-Formylphenylboric acid | HCID 21940015 | — |
| Edukt | 2-(Trimethylsilyl)ethyl 4-{[(trifluoromethyl)sulfonyl]oxy}isoquinoline-6-carboxylate | HCID 58495760 | — |
| Produkt | 2-(Trimethylsilyl)ethyl 4-(4-formylphenyl)isoquinoline-6-carboxylate | HCID 86661966 | 79,7% |
Reaktionsschritte
Using 2-(trimethylsilyl)ethyl 4-{[(trifluoromethyl)sulfonyl]oxy}isoquinoline-6-carboxylate (600 mg, 1.42 mmol) and 4-formylphenylboric acid (320 mg, 2.14 mmol), the desired title compound (427 mg, yield 79%) was obtained by the same method as in Example 8 (8a).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08410273B2 |
| Quelldatensatz | uspto-grants-2013_04 |
| ORD ID | ord-0fadfcfdb6754866851a45ba02dd125c |
| Quellennotiz | uspto-grants-2013_04 |