HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-methyl-N-(4-{[4-(methylamino)-3-nitrophenyl]oxy}pyridin-2-yl)piperidine-4-carboxamide → N-(4-{[3-amino-4-(methylamino)phenyl]oxy}pyridin-2-yl)-1-methylpiperidine-4-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-methyl-N-(4-{[4-(methylamino)-3-nitrophenyl]oxy}pyridin-2-yl)piperidine-4-carboxamide | HCID 69003266 | — |
| Katalysator | Lindlars catalyst | HCID 131709914 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | N-(4-{[3-amino-4-(methylamino)phenyl]oxy}pyridin-2-yl)-1-methylpiperidine-4-carboxamide | HCID 69004595 | — |
Reaktionsschritte
The mixture containing 1-methyl-N-(4-{[4-(methylamino)-3-nitrophenyl]oxy}pyridin-2-yl)piperidine-4-carboxamide in methanol with catalytic amount of Lindlar's catalyst was hydrogenated to yield N-(4-{[3-amino-4-(methylamino)phenyl]oxy}pyridin-2-yl)-1-methylpiperidine-4-carboxamide. MS: MH+=356.2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08415382B2 |
| Quelldatensatz | uspto-grants-2013_04 |
| ORD ID | ord-44f53979c6994f69ba7f3713f4e4c777 |
| Quellennotiz | uspto-grants-2013_04 |