Cyclododecanamine → 5-Chloro-2-[(([2-(cyclododecylamino)-2-oxoethyl]sulfanyl)acetyl)amino]benzoic acid
Reaktionsgleichung
[CH:1]1([NH2:13])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([NH:21][C:22](=[O:29])[CH2:23][S:24][CH2:25][C:26](O)=[O:27])=[C:17]([C:30]([O:32]C)=[O:31])[CH:16]=1>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([NH:21][C:22](=[O:29])[CH2:23][S:24][CH2:25][C:26]([NH:13][CH:1]2[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)=[O:27])=[C:17]([CH:16]=1)[C:30]([OH:32])=[O:31]Komponenten
3
Versuchsvorschrift
Using the same method as in Example 1-(ii), cyclododecylamine was reacted with the [(2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethyl)sulfanyl]acetic acid obtained in Example 12-(i) to give 5-chloro-2-[(([2-(cyclododecylamino)-2-oxoethyl]sulfanyl)acetyl)amino]benzoic acid.methyl ester (yield: 95%).
Quellen und Nachweise
- ORD-Eintrag
- ord-2a81bad3b65142baa17296efccaf7681
- Quelldatensatz