HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(S)-1-Phenyl-3-propanolamine → (2S)-N-[(1S)-3-hydroxy-1-phenylpropyl]-3-[(4-tert-pentylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (S)-1-Phenyl-3-propanolamine | HCID 2734520 | — |
| Edukt | 3-[(4-Tert-pentylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxylic acid | HCID 68623277 | — |
| Produkt | (2S)-N-[(1S)-3-hydroxy-1-phenylpropyl]-3-[(4-tert-pentylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxamide | HCID 57462299 | — |
Reaktionsschritte
Following the general strategies and protocols outlined in Example 1, starting from 3-[(4-tert-pentylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxylic acid (Intermediate 8) and commercial (3S)-3-amino-3-phenyl-1-propanol, the title compound was obtained in 99% purity by HPLC.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08415480B2 |
| Quelldatensatz | uspto-grants-2013_04 |
| ORD ID | ord-bb98d9dfce334673abd918c39224dd97 |
| Quellennotiz | uspto-grants-2013_04 |