2,3-Dichloropyridine → (6-tert-Butyl-pyridin-3-yl)-[6-(3-chloro-pyridin-2-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl]-amine

HRID 19650

Reaktionsgleichung

Reaktionsgleichung von HRID 19650
[N:1]1[C:6]2[CH2:7][CH2:8][NH:9][CH2:10][C:5]=2[C:4]([NH:11][C:12]2[CH:13]=[N:14][C:15]([C:18]([CH3:21])([CH3:20])[CH3:19])=[CH:16][CH:17]=2)=[N:3][CH:2]=1.Cl[C:23]1[C:28]([Cl:29])=[CH:27][CH:26]=[CH:25][N:24]=1>>[C:18]([C:15]1[N:14]=[CH:13][C:12]([NH:11][C:4]2[C:5]3[CH2:10][N:9]([C:23]4[C:28]([Cl:29])=[CH:27][CH:26]=[CH:25][N:24]=4)[CH2:8][CH2:7][C:6]=3[N:1]=[CH:2][N:3]=2)=[CH:17][CH:16]=1)([CH3:21])([CH3:20])[CH3:19]

Komponenten

3

Edukt 2

HCID 169882,3-DichloropyridineHCID 59346577(5,6,7,8-Tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-(6-tert-butyl-pyridin-3-yl)-amine

Produkt 1

HCID 59346546(6-tert-Butyl-pyridin-3-yl)-[6-(3-chloro-pyridin-2-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl]-amine

Versuchsvorschrift

The title compound was prepared according to the procedure given for Compound 1C by reacting (5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-(6-tert-butyl-pyridin-3-yl)-amine with 2,3-dichloropyridine to give the desired compound as an off-white powder.

Aufarbeitung

  1. customThe title compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-08369462b61f4121b5919fa794c65df0
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07745451B2

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