Ethyl 4,4-difluoro-4-phenylbutanoate → Ethyl 4,4,5,5-tetrafluoro-6-(3-phenylpropoxy)hexanoate
Reaktionsgleichung
[F:1][C:2]([F:24])([C:10]([F:23])([F:22])[CH2:11][O:12][CH2:13]/[CH:14]=[CH:15]/[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)/[CH:3]=[CH:4]/[C:5]([O:7][CH2:8][CH3:9])=[O:6].FC(F)(C1C=CC=CC=1)CCC(OCC)=O>>[F:1][C:2]([F:24])([C:10]([F:22])([F:23])[CH2:11][O:12][CH2:13][CH2:14][CH2:15][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[CH2:3][CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6]Komponenten
3
Versuchsvorschrift
Obtained from Intermediate 39 (1.2 g, 3.46 mmol) by the procedure described in Intermediate 21. Ethyl 4,4,5,5-tetrafluoro-6-(3-phenylpropoxy)hexanoate was obtained (1.0 g, 82%) as oil.
Quellen und Nachweise
- ORD-Eintrag
- ord-86aa78d0fce14300a4b36391ed36613d
- Quelldatensatz
- uspto-grants-2013_04