3-Nitrobenzenesulfonyl chloride → HCID 59152956, Verbindung
Reaktionsgleichung
[CH2:1]([O:3][C:4](=[O:16])[CH2:5][N:6]1[C:14]2[CH2:13][CH2:12][CH2:11][CH:10]([NH2:15])[C:9]=2[CH:8]=[N:7]1)[CH3:2].[N+:17]([C:20]1[CH:21]=[C:22]([S:26](Cl)(=[O:28])=[O:27])[CH:23]=[CH:24][CH:25]=1)([O-:19])=[O:18]>>[CH2:1]([O:3][C:4](=[O:16])[CH2:5][N:6]1[C:14]2[CH2:13][CH2:12][CH2:11][CH:10]([NH:15][S:26]([C:22]3[CH:23]=[CH:24][CH:25]=[C:20]([N+:17]([O-:19])=[O:18])[CH:21]=3)(=[O:27])=[O:28])[C:9]=2[CH:8]=[N:7]1)[CH3:2]Komponenten
3
Versuchsvorschrift
Starting with (4-amino-4,5,6,7-tetrahydro-indazol-1-yl)-acetic acid ethyl ester and 3-nitro-benzenesulfonyl chloride using the method analogous to the one described above for example 1-1, [4-(3-nitro-benzenesulfonylamino)-4,5,6,7-tetrahydro-indazol-1-yl]-acetic acid ethyl ester (519 mg, 63.6%) was obtained as a white solid. MS cald. for C17H20N4O6S 408, obsd. (ESI+) [(M+H)+] 409.
Quellen und Nachweise
- ORD-Eintrag
- ord-bd39ca0dda9a45a6b264f0fe16fc9ebb
- Quelldatensatz
- uspto-grants-2013_04