1-(2-Propynyl)piperazine → HCID 21492752, Verbindung
Reaktionsgleichung
Cl[CH:2]1[C:8]2[CH:9]=[C:10]([F:13])[CH:11]=[CH:12][C:7]=2[S:6][C:5]2[CH:14]=[C:15]([CH3:18])[CH:16]=[CH:17][C:4]=2[CH2:3]1.[CH2:19]([N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)[C:20]#[CH:21]>>[CH3:18][C:15]1[CH:16]=[CH:17][C:4]2[CH2:3][CH:2]([N:25]3[CH2:26][CH2:27][N:22]([CH2:19][C:20]#[CH:21])[CH2:23][CH2:24]3)[C:8]3[CH:9]=[C:10]([F:13])[CH:11]=[CH:12][C:7]=3[S:6][C:5]=2[CH:14]=1Komponenten
3
Versuchsvorschrift
In a manner analogous to that described in Example 1, from 10-chloro-10,11-dihydro-3-methyl-8-fluoro-dibenzo[b,f]thiepin and N-(2-propynyl)-piperazine there is obtained 1-[10,11-dihydro-3-methyl-8-fluoro-dibenzo[b,f]thiepin-10-yl]-4-(2-propynyl)-piperazine, the dimethanesulfonate of which melts at 168°-174° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-53e152fb228b4aedaa27fb26c2c427e9
- Quelldatensatz
- uspto-grants-1976_12