Hydrochloric Acid → 4-Hydroxy-4-methylaminomethylpiperidine dihydrochloride

HRID 1974870Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1974870
[OH:1][C:2]1([CH2:13][NH:14][CH3:15])[CH2:7][CH2:6][N:5](C(OCC)=O)[CH2:4][CH2:3]1.[ClH:16]>>[ClH:16].[ClH:16].[OH:1][C:2]1([CH2:13][NH:14][CH3:15])[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1

Komponenten

3

Edukt 2

HCID 313Hydrochloric AcidHCID 19382193HCID 19382193, Verbindung

Produkt 1

HCID 193821784-Hydroxy-4-methylaminomethylpiperidine dihydrochloride

Versuchsvorschrift

3 g (13.9 mmol) of ethyl 4-hydroxy-4-methylaminomethylpiperidine-1-carboxylate are heated overnight under reflux with 30 ml of concentrated hydrochloric acid. The product is concentrated, and the crystals are stirred with acetone, filtered off with suction and dried in a vacuum desiccator over P4O10.

Aufarbeitung

  1. concentrationThe product is concentrated
  2. filtrationfiltered off with suction
  3. dry with materialdried in a vacuum desiccator over P4O10

Quellen und Nachweise

ORD-Eintrag
ord-2cd26c5cef15468881d1ed8a2153964b
Quelldatensatz
uspto-grants-1994_02
Patentnummer
US05284842

Notizen zur Reaktion

Wird geladen…