Chloroform → HCID 18766188, Verbindung

HRID 19749

Reaktionsgleichung

Reaktionsgleichung von HRID 19749
[NH2:1][O:2][CH2:3][CH:4]([OH:12])[CH2:5][N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1.C(Cl)(Cl)Cl.[CH2:17]([N:24]=[C:25]=[O:26])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]>>[OH:12][CH:4]([CH2:5][N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[CH2:3][O:2][NH:1][C:25]([NH:24][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])=[O:26]

Komponenten

4

Edukt 3

HCID 6212ChloroformHCID 138341n-Heptyl isocyanateHCID 187662101-(Aminooxy)-3-(piperidin-1-yl)propan-2-ol

Produkt 1

HCID 18766188HCID 18766188, Verbindung

Versuchsvorschrift

To the solution of 1.23 g (7.1 mmol) of l-aminooxy-2-hydroxy-3-(1-piperidinyl)-propane dissolved in 20 ml of chloroform 1.0 g (7.1 mmol) of heptyl isocyanate was added and the reaction mixture was stirred for 20 hours. Solvent was evaporated in vacuum and the residue was purified by chromatography to give pure colorless oil. White crystalline product was obtained by triturating with petroleum ether.

Aufarbeitung

  1. additionwas added
  2. customSolvent was evaporated in vacuum
  3. customthe residue was purified by chromatography
  4. customto give pure colorless oil
  5. customWhite crystalline product was obtained
  6. customby triturating with petroleum ether

Quellen und Nachweise

ORD-Eintrag
ord-5d41a87368eb46de9294345e9b841d10
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07745465B2

Verknüpfte Notizen

Wird geladen…