2-Methylbutyl isothiocyanate → HCID 21999995, Verbindung
Reaktionsgleichung
Cl.[NH2:2][C:3]1[CH:7]=[C:6]([Cl:8])[S:5][C:4]=1[S:9]([NH2:12])(=[O:11])=[O:10].[CH3:13][CH:14]([CH2:19][CH3:20])[CH2:15][N:16]=[C:17]=[S:18]>>[NH2:2][C:3]1[CH:7]=[C:6]([Cl:8])[S:5][C:4]=1[S:9]([NH:12][C:17]([NH:16][CH2:15][CH:14]([CH3:13])[CH2:19][CH3:20])=[S:18])(=[O:10])=[O:11]Komponenten
3
Versuchsvorschrift
The title compound was prepared from 3-amino-5-chlorothiophene-2-sulfonamide hydrochloride and 2-methylbutyl isothiocyanate by a procedure analogous to the procedure described in example 3-a (yield 28%); mp 116.5-118° C., 1H-NMR (DMSO-d6): δ0.8 (2 d, 6H, 2×CH3), 1.10 (m, 1H), 1.30 (m, 1H), 1.65 (m, 1H), 3.40 (m, 2H+HDO, CH2), 6.45 (br, 2H, NH2), 6.65 (s, 1H, H-4), 8.25 (br t, 1H, NH), 11.3 (br s, 1H).
Quellen und Nachweise
- ORD-Eintrag
- ord-749c2b46276e43188e510b595973cbe6
- Quelldatensatz
- uspto-grants-2001_05