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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1975927Erstellt: 26. Oktober 2026

Cyclopentyl isothiocyanate → N-[5-Chloro-3-(cyclopentylthiocarbamoyl)sulfamoylthiophen-2-yl]acetamide

https://huagongshe.com/reaction/1975927

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktCyclopentyl isothiocyanateHCID 141792—
EduktN-(5-chloro-3-sulfamoylthiophen-2-yl)-acetamideHCID 22000000—
ProduktN-[5-Chloro-3-(cyclopentylthiocarbamoyl)sulfamoylthiophen-2-yl]acetamideHCID 21999997—

Reaktionsschritte

The title compound was prepared from N-(5-chloro-3-sulfamoylthiophen-2-yl)-acetamide and cyclopentyl isothiocyanate by a procedure analogous to the procedure described in example 15a (yield of crude product: 93%); 1H-NMR (DMSO-d6): δ1.3-2.0 (m, 8H, (CH2)4), 2.28 (s, 3H, CH3), 4.32 (sext, 1H, CH), 7.16 (s, 1H, H-4), 8.48 (br d, 1H, NH), 10.23 (br s, 1H, NH).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06225310B1
Quelldatensatzuspto-grants-2001_05
ORD IDord-54ab9b7d65824b2a83913917efb5b319
Quellennotizuspto-grants-2001_05