HCID 21996975, Verbindung → HCID 21996970, Verbindung
Reaktionsgleichung
BrC1C=CC(O)=C(C=1)C(C1C=CC(C)=CC=1)=O.[Br:18][C:19]1[C:20]([CH3:36])=[CH:21][C:22]([O:34]C)=[C:23]([CH:33]=1)[C:24]([C:26]1[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=1)=[O:25]>>[Br:18][C:19]1[C:20]([CH3:36])=[CH:21][C:22]([OH:34])=[C:23]([CH:33]=1)[C:24]([C:26]1[CH:27]=[CH:28][C:29]([CH3:32])=[CH:30][CH:31]=1)=[O:25]Komponenten
3
Versuchsvorschrift
Employing the same general procedure as for the 5-bromo-2-hydroxy-4′-methylbenzophenone (Compound K), 319 mg (1.0 mmol) of 5-bromo-2-methoxy-4-methyl-4′-methylbenzophenone (Compound I) was converted into the title compound using 2.4 mL (2.4 mmol) of boron tribromide (1M in dichloromethane) and 10 mL of dichloromethane. Purification by flash chromatography (silica, 10% ethyl acetate in hexane) gave the title compound as a pale yellow solid.
Quellen und Nachweise
- ORD-Eintrag
- ord-59a5fdae4bd549cd9c1e5a0104dfef28
- Quelldatensatz
- uspto-grants-2001_05
- DOI