Ethyl cyanoacetate → Ethyl 2-cyano-3-hydroxy-4,4,5,5,5-pentafluoro-2-pentenoate

Beteiligte Stoffe

Reaktionsschritte

To 20 ml of tetrahydrofuran, 3.39 g (30 mmol) of ethyl cyanoacetate and 6.06 g (60 mmol) of triethylamine were dissolved and stirred at room temperature. Successively, 5.47 g (30 mmol) of pentafluoropropionyl chloride was dropwise added and stirred for 5 hours at room temperature. However, formation of desired product could not be confirmed.

Herkunft & Nachweise