HCID 21996968, Verbindung → HCID 21996988, Verbindung
Reaktionsgleichung
BrC1C=CC(O)=C(C=1)C(C1C=CC(C)=CC=1)=O.[Br:18][C:19]1[CH:20]=[CH:21][C:22]([O:34]C)=[C:23]([CH:33]=1)[C:24]([C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([CH3:32])[CH:27]=1)=[O:25]>>[Br:18][C:19]1[CH:20]=[CH:21][C:22]([OH:34])=[C:23]([CH:33]=1)[C:24]([C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([CH3:32])[CH:27]=1)=[O:25]Komponenten
3
Versuchsvorschrift
Employing the same general procedure as for the preparation 5-bromo-2-hydroxy-4′-methylbenzophenone (Compound K), 533 mg (1.7 mmol) of 5-bromo-2-methoxy-3′-methylbenzophenone (Compound J) was converted into the title compound using 2.6 mL (2.6 mmol) of boron tribromide (1M in dichloromethane) and 15 mL of dichloromethane. Purification by flash chromatography (silica, 10% ethyl acetate in hexane) gave the title compound as a white solid.
Quellen und Nachweise
- ORD-Eintrag
- ord-59fbbb9e1f2143c8b64238349a3ef44b
- Quelldatensatz
- uspto-grants-2001_05
- DOI