Hydrochloric Acid → HCID 21994007, Verbindung

HRID 1978496Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1978496
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16](=[O:31])/[CH:17]=[CH:18]/[C:19]2[S:29][C:28]3[N:30]4[C:21](=[CH:22][N:23]=[C:24]4[CH:25]=[CH:26][CH:27]=3)[CH:20]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:32]>C(O)C>[ClH:32].[ClH:32].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16](=[O:31])/[CH:17]=[CH:18]/[C:19]2[S:29][C:28]3[N:30]4[C:21](=[CH:22][N:23]=[C:24]4[CH:25]=[CH:26][CH:27]=3)[CH:20]=2)[CH2:10][CH2:9]1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 21993956HCID 21993956, Verbindung

Produkt 1

HCID 21994007HCID 21994007, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

To the above crude (E)-5-[1-(tert-butoxycarbonyl)-piperidin-4-yl]-1-(5-thia-1,8b-diazaacenaphthylen-4-yl)-1-penten-3-one was added 5 ml of concentrated hydrochloric acid and the mixture was stirred at room temperature for 15 minutes. To this reaction mixture was added ethanol, followed by stirring, and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

Aufarbeitung

  1. stirringby stirring
  2. filtrationthe resulting precipitate was recovered by filtration
  3. washrinsed serially with ethanol and diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-b8d82418373b46a2af9812f860e7a1a3
Quelldatensatz
uspto-grants-2001_05
Patentnummer
US06235731B1

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