Hydrochloric Acid → HCID 21993711, Verbindung

HRID 1978500Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1978500
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][S:15](/[CH:18]=[CH:19]/[C:20]2[S:30][C:29]3[N:31]4[C:22](=[CH:23][N:24]=[C:25]4[CH:26]=[CH:27][CH:28]=3)[CH:21]=2)(=[O:17])=[O:16])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:32]>C(O)C>[ClH:32].[ClH:32].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][S:15](/[CH:18]=[CH:19]/[C:20]2[S:30][C:29]3[N:31]4[C:22](=[CH:23][N:24]=[C:25]4[CH:26]=[CH:27][CH:28]=3)[CH:21]=2)(=[O:17])=[O:16])[CH2:10][CH2:9]1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 86756772HCID 86756772, Verbindung

Produkt 1

HCID 21993711HCID 21993711, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

To the above crude (E)-4-[2-[1-(tert-butoxycarbon-yl)piperidin-4-ylmethanesulfonyl]vinyl]-5-thia-1,8b-diazaacenaphthylene was added 3 ml of concentrated hydrochloric acid, and the mixture was stirred at room temperature for 10 minutes. To this reaction mixture was added ethanol, and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

Aufarbeitung

  1. filtrationthe resulting precipitate was recovered by filtration
  2. washrinsed serially with ethanol and diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-9c1b6533d2bb474ebdcd268d739f565c
Quelldatensatz
uspto-grants-2001_05
Patentnummer
US06235731B1

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