Hydrochloric Acid → HCID 21993996, Verbindung

HRID 1978502Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1978502
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH:13]([CH2:16][S:17](/[CH:20]=[CH:21]/[C:22]3[S:32][C:31]4[N:33]5[C:24](=[CH:25][N:26]=[C:27]5[CH:28]=[CH:29][CH:30]=4)[CH:23]=3)(=[O:19])=[O:18])[CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:34]>CO>[ClH:34].[ClH:34].[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([CH2:16][S:17](/[CH:20]=[CH:21]/[C:22]3[S:32][C:31]4[N:33]5[C:24](=[CH:25][N:26]=[C:27]5[CH:28]=[CH:29][CH:30]=4)[CH:23]=3)(=[O:19])=[O:18])[CH2:14][CH2:15]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 21993869HCID 21993869, Verbindung

Produkt 1

HCID 21993996HCID 21993996, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

In 2 ml of methanol was dissolved 0.418 g of (E)-4-[2-[1-(3-phenylpropan-1-yl)piperidin-4-ylmethanesulfonyl]vinyl]-5-thia-1,8b-diazaacenaphthylene, followed by addition of a stoichiometric excess of methanolic hydrochloric acid, and the mixture was stirred for 10 minutes. This reaction mixture was concentrated and crystallized from ethanol-diethyl ether to provide the title compound.

Aufarbeitung

  1. concentrationThis reaction mixture was concentrated
  2. customcrystallized from ethanol-diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-c223195d5ecf48a1987f9c57a32793af
Quelldatensatz
uspto-grants-2001_05
Patentnummer
US06235731B1

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