Methyl iodide → HCID 20437408, Verbindung

HRID 1980090Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1980090
[OH:1][CH:2]([CH2:9][NH:10][S:11]([C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH2:3][N:4]1[CH2:8][CH2:7][CH2:6][CH2:5]1.[CH3:24][I:25]>CO>[I-:25].[OH:1][CH:2]([CH2:9][NH:10][S:11]([C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH2:3][N+:4]1([CH3:24])[CH2:8][CH2:7][CH2:6][CH2:5]1

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 20437405HCID 20437405, Verbindung

Produkt 1

HCID 20437408HCID 20437408, VerbindungAusbeute 545,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of 1-[2-hydroxy-3-(1-naphthalenesulphonamido)propyl]pyrrolidine (2 g; 0.0005 mol) in methanol (50 ml) was added methyl iodide (6.9 g; 0.05 mol). The mixture was left at room temperature 12 hours. The reaction mixture was evaporated to dryness and the residue was recrystallized from ethanol (20 ml) to obtain the product (1.3 g).

Aufarbeitung

  1. customThe reaction mixture was evaporated to dryness
  2. customthe residue was recrystallized from ethanol (20 ml)

Quellen und Nachweise

ORD-Eintrag
ord-dfe7be1f650f49aaa7511649034dfcf6
Quelldatensatz
uspto-grants-1984_11
Patentnummer
US04485108

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