(S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-2-methylpropanoic acid → Metyrosine

Beteiligte Stoffe

Reaktionsschritte

200 milligrams of (S)-N-carbobenzyloxy-α-methyltyrosine is mixed together with 20 milligrams of 10 percent palladium on carbon catalyst and 10 milliliters of methanol and the mixture subjected to hydrogen at a pressure of 40 psi for several hours. Thereafter, the catalyst is removed and the filtrate concentrated to obtain a (S)-α-methyltyrosine product.

Herkunft & Nachweise