HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethylamine → 4-Cyclohexyl-2-[(dimethylamino)methyl]-2,3-dihydropyrido[3,2-f][1,4]oxazepin-5(4H)-one oxalate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethylamine | HCID 674 | — |
| Edukt | Oxalic Acid | HCID 971 | — |
| Edukt | chloromethyl-4-cyclohexyl-2,3-dihydropyrido[3,2-f][1,4]oxazepin-5(4H)-one | HCID 13729322 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | 4-Cyclohexyl-2-[(dimethylamino)methyl]-2,3-dihydropyrido[3,2-f][1,4]oxazepin-5(4H)-one oxalate | HCID 21271464 | — |
Reaktionsschritte
Utilizing the procedure of Example 10, 2-(chloromethyl)-4-cyclohexyl-2,3-dihydropyrido[3,2-f][1,4]oxazepin-5(4H)-one (Intermediate 35) is reacted with 40% aqueous dimethylamine and treated with oxalic acid in isopropyl alcohol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04592866 |
| Quelldatensatz | uspto-grants-1986_06 |
| ORD ID | ord-a6e14d0f685144d9b9d6c769f1d5cf31 |
| Quellennotiz | uspto-grants-1986_06 |