HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(3-O-Acetyl-5-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine → Fmau
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(3-O-Acetyl-5-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine | HCID 54100196 | — |
| Lösungsmittel | Ammonia | HCID 222 | — |
| Produkt | Fmau | HCID 72327 | 83,3% |
Reaktionsschritte
1-(3-O-Acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)thymine (150 mg) is dissolved in saturated methanolic ammonia (15 ml), and the mixture left standing for 16 hours. The solvent is removed by evaporation in vacuo, and the residue crystallized from water to give 80 mg of 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)thymine, m.p. 185°-185.5°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04594339 |
| Quelldatensatz | uspto-grants-1986_06 |
| ORD ID | ord-96132df5c92049749906da17a2d68cee |
| Quellennotiz | uspto-grants-1986_06 |