[CH2:1]([CH2:4][CH:5]([OH:14])[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7])[CH:2]=[CH2:3].[OH-].[K+].CO.Cl>C(O)CCC>[OH:14][CH:5]([CH2:4][CH:1]=[CH:2][CH3:3])[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7]Then to 233 grams of 3-allyl-2-hydroxypropiophenone are added 212 grams of potassium hydroxide, 200 ml of methanol and 1100 ml of n-butanol and the mixture is heated to reflux for twenty four hours. It is then poured into ice water, acidified with concentrated hydrochloric acid, crystals separated out therefrom are collected by filtration, washed with water and recrystallized from methanol to give 105 grams of 2-hydroxy-3-propenylpropiophenone, yellow needles, melting point 83° to 85° C.
Wird geladen…
