Sulfuric Acid → Benzylsulfamic acid

HRID 1982164Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1982164
[CH2:1]([N:8]=C=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:11](=O)(=[O:14])([OH:13])[OH:12]>[N+](C)([O-])=O>[CH2:1]([NH:8][S:11](=[O:13])(=[O:12])[OH:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 1118Sulfuric AcidHCID 76639Benzyl isocyanate

Produkt 1

HCID 12649342Benzylsulfamic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6375NitromethaneLösungsmittel

Versuchsvorschrift

Benzylisocyanate (13.3 g) is added dropwise to a stirred mixture of nitromethane (160 ml) and 15% fuming sulfuric acid (5.4 ml) at about 10° C. The reaction mixture is refluxed for about one hour, cooled to RT and the solid filtered and washed with nitromethene. The solid is suspended in ether, filtered, dried and used as a crude solid in the next step.

Aufarbeitung

  1. temperatureThe reaction mixture is refluxed for about one hour
  2. filtrationthe solid filtered
  3. washwashed with nitromethene
  4. filtrationfiltered
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-c811b7d3305548a083ba6b5e2443a7a8
Quelldatensatz
uspto-grants-1986_06
Patentnummer
US04595683

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