Allyl bromide → 4-Hydroxy-1-phenyl-3-(prop-2-en-1-yl)-1,8-naphthyridin-2(1H)-one
Reaktionsgleichung
BrCCC=C.C(Br)C=C.[CH2:10]([C:14]1[C:15](=[O:31])[N:16]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:17]2[C:22]([C:23]=1[OH:24])=[CH:21][CH:20]=[CH:19][N:18]=2)[CH2:11][CH:12]=C>>[OH:24][C:23]1[C:22]2[C:17](=[N:18][CH:19]=[CH:20][CH:21]=2)[N:16]([C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)[C:15](=[O:31])[C:14]=1[CH2:10][CH:11]=[CH2:12]Komponenten
4
Versuchsvorschrift
In a similar manner, substitute 4-bromo-1-butene for allyl bromide in part B(1) of Preparation 1 to prepare 3-(3-butenyl)-4-hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one.
Quellen und Nachweise
- ORD-Eintrag
- ord-fcdbbf861f014eecb2f84dc4981cd568
- Quelldatensatz
- uspto-grants-1986_06
- DOI