HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Imidazole → 8-Phenyl-5,6-dihydroimidazo[1,2-a]pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Imidazole | HCID 795 | — |
| Edukt | Cyclopropyl phenyl ketone | HCID 77029 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 8-Phenyl-5,6-dihydroimidazo[1,2-a]pyridine | HCID 13764012 | — |
Reaktionsschritte
Combine 25 g (0.17 mol) of cyclopropyl phenyl ketone with 50 g (0.73 mol) of imidazole, and heat to 200° C. for 18 hr. Isolation from 200 g of silica gel using methylene chloride, followed by crystallization from ether provides the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04596872 |
| Quelldatensatz | uspto-grants-1986_06 |
| ORD ID | ord-4545ff0b998542439203efaef455be6b |
| Quellennotiz | uspto-grants-1986_06 |