Thionyl Chloride → 4-bromo-1-(chloromethyl)-3-(pentafluoroethyl)-1H-pyrazole

HRID 1983046Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1983046
[Br:1][C:2]1[C:3]([C:9]([F:15])([F:14])[C:10]([F:13])([F:12])[F:11])=[N:4][N:5]([CH2:7]O)[CH:6]=1.S(Cl)([Cl:18])=O>ClCCl>[Br:1][C:2]1[C:3]([C:9]([F:15])([F:14])[C:10]([F:13])([F:12])[F:11])=[N:4][N:5]([CH2:7][Cl:18])[CH:6]=1

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 231491334-bromo-3-(pentafluoroethyl)-1H-pyrazole-1-ylmethanol

Produkt 1

HCID 231491944-bromo-1-(chloromethyl)-3-(pentafluoroethyl)-1H-pyrazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

6.49 g of 4-bromo-3-(pentafluoroethyl)-1H-pyrazole-1-ylmethanol was dissolved to 60 ml of dichloromethane. 3.2 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 6.84 g of 4-bromo-1-(chloromethyl)-3-(pentafluoroethyl)-1H-pyrazole.

Aufarbeitung

  1. concentrationThe reaction mixture was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-96d77e08646f48fbbae403a54c833d69
Quelldatensatz
uspto-grants-2009_06
Patentnummer
US07541374B2

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