2-(4-Phenylpiperazin-1-yl)ethan-1-amine → 1-t-Butyl-5-(4-chlorophenyl)-3-[2-(4-phenylpiperazin-1-yl)ethyl]aminomethylpyrazole
Reaktionsgleichung
[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:13][CH2:14][NH2:15])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([C:23]2[N:27]([C:28]([CH3:31])([CH3:30])[CH3:29])[N:26]=[C:25]([CH:32]=O)[CH:24]=2)=[CH:19][CH:18]=1>>[C:28]([N:27]1[C:23]([C:20]2[CH:19]=[CH:18][C:17]([Cl:16])=[CH:22][CH:21]=2)=[CH:24][C:25]([CH2:32][NH:15][CH2:14][CH2:13][N:10]2[CH2:9][CH2:8][N:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[CH2:12][CH2:11]2)=[N:26]1)([CH3:31])([CH3:30])[CH3:29]Komponenten
3
Versuchsvorschrift
Compound 11 was prepared using the same method as that of Example 1 except that 4-phenylpiperazin-1-ylethylamine and 5-(4-chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde were used.
Quellen und Nachweise
- ORD-Eintrag
- ord-3bf992771850452f94fae902b7966328
- Quelldatensatz
- uspto-grants-2009_06
- Patentnummer
- US07544686B2
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