7-Aminoquinoline → HCID 11372005, Verbindung
Reaktionsgleichung
[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[C:7]([C:11]([OH:13])=O)[NH:8]2)=[CH:4][CH:3]=1.[NH2:14][C:15]1[CH:24]=[C:23]2[C:18]([CH:19]=[CH:20][CH:21]=[N:22]2)=[CH:17][CH:16]=1>>[N:22]1[C:23]2[C:18](=[CH:17][CH:16]=[C:15]([NH:14][C:11]([C:7]3[NH:8][C:9]4[C:5]([CH:6]=3)=[CH:4][CH:3]=[C:2]([Br:1])[CH:10]=4)=[O:13])[CH:24]=2)[CH:19]=[CH:20][CH:21]=1Komponenten
3
Versuchsvorschrift
This material was prepared analogous to the procedure described for Example 6(b). 6-Bromo-1H-indole-2-carboxylic acid (208 mg, 0.87 mmol, Asymchem) reacted with 7-amino-quinoline (125 mg, 0.87 mmol, prepared according to the procedure described in WO03099284) to give the title compound as a light-brown amorphous solid. MS (ESI, pos. ion) m/z: 366 (M+1).
Aufarbeitung
- customThis material was prepared analogous to the procedure
- customprepared
Quellen und Nachweise
- ORD-Eintrag