HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(3-Aminopropyl)-4-methylpiperazine → [5-Chloro-4-(7-methoxybenzo[b]thiophen-2-yl)-pyrimidin-2-yl]-[3-(4-methyl-piperazin-1-yl)-propyl]-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(3-Aminopropyl)-4-methylpiperazine | HCID 78328 | — |
| Edukt | [4-(Benzo[b]thiophen-2-yl)-pyrimidin-2-yl]-[3-(4-methylpiperazin-1-yl)-propyl]-amine tri-hydrochloride | HCID 68855962 | — |
| Edukt | 2,5-Dichloro-4-(7-methoxybenzo[b]thiophen-2-yl)-pyrimidine | HCID 86625369 | — |
| Produkt | [5-Chloro-4-(7-methoxybenzo[b]thiophen-2-yl)-pyrimidin-2-yl]-[3-(4-methyl-piperazin-1-yl)-propyl]-amine | HCID 68857035 | — |
Reaktionsschritte
Using the method of [4-(benzo[b]thiophen-2-yl)-pyrimidin-2-yl]-[3-(4-methylpiperazin-1-yl)-propyl]-amine tri-hydrochloride, the title compound is prepared from 2,5-dichloro-4-(7-methoxybenzo[b]thiophen-2-yl)-pyrimidine and 1-(3-aminopropyl)-4-methylpiperazine and isolated as a yellowish solid. ES+(m/z) 432(35Cl) and 434(37Cl) [M+H].
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07547691B2 |
| Quelldatensatz | uspto-grants-2009_06 |
| ORD ID | ord-e5d30b38bc48464db4d04380ac71369c |
| Quellennotiz | uspto-grants-2009_06 |