3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole → N,N-dimethyl-3-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}propanamide

HRID 1988657

Reaktionsgleichung

Reaktionsgleichung von HRID 1988657
Br[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([N:12]([CH3:14])[CH3:13])=[O:11])=[CH:4][CH:3]=1.[F:15][C:16]([F:27])([F:26])[C:17]1[C:25]2[CH2:24][CH2:23][CH2:22][CH2:21][C:20]=2[NH:19][N:18]=1>>[CH3:13][N:12]([CH3:14])[C:10](=[O:11])[CH2:9][CH2:8][C:5]1[CH:6]=[CH:7][C:2]([N:19]2[C:20]3[CH2:21][CH2:22][CH2:23][CH2:24][C:25]=3[C:17]([C:16]([F:15])([F:27])[F:26])=[N:18]2)=[CH:3][CH:4]=1

Komponenten

3

Edukt 2

HCID 28028633-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazoleHCID 577628213-(4-bromophenyl)-N,N-dimethylpropanamide

Produkt 1

HCID 24827140N,N-dimethyl-3-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}propanamide

Versuchsvorschrift

The title compound was prepared from 3-(4-bromophenyl)-N,N-dimethylpropanamide and 3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole using a similar procedure to that described for Example 1.

Quellen und Nachweise

ORD-Eintrag
ord-8b249cfe61b748ceb0fca5d6154b19b0
Quelldatensatz
uspto-grants-2010_01
Patentnummer
US07642256B2

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