2-Chloro-4-trifluoromethyl-6-(4-trifluoromethylphenyl)-pyridine → 2-(3-Chloro-[1,2,4]triazol-1-yl)-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridine
Reaktionsgleichung
Cl[C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=2)[N:3]=1.[Cl:22][C:23]1[N:27]=[CH:26][NH:25][N:24]=1>>[Cl:22][C:23]1[N:27]=[CH:26][N:25]([C:2]2[CH:7]=[C:6]([C:8]([F:11])([F:9])[F:10])[CH:5]=[C:4]([C:12]3[CH:13]=[CH:14][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:16][CH:17]=3)[N:3]=2)[N:24]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared from 2-chloro-4-trifluoromethyl-6-(4-trifluoromethylphenyl)-pyridine (example A.17) (1.628 g, 5.0 mmol) and commercially available 3-chloro-1H-(1,2,4)triazole (0.776 g, 7 mmol) according to the general procedure IVa. Obtained as a white solid (1.651 g, 84%). MS (ISP) 393.1 [(M+H)+] and 395 [(M+2+H)+].
Quellen und Nachweise
- ORD-Eintrag
- ord-53dade500e3c40ed9ab4a36ab7806340