HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(1-Piperidinylsulfonyl)piperazine → [5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-[4-(piperidine-1-sulfonyl)-piperazin-1-yl]-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(1-Piperidinylsulfonyl)piperazine | HCID 285501 | — |
| Edukt | [5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-(4-methanesulfonyl-piperazin-1-yl)-methanone | HCID 68538245 | — |
| Produkt | [5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-[4-(piperidine-1-sulfonyl)-piperazin-1-yl]-methanone | HCID 68536516 | 87% |
Reaktionsschritte
The title compound was synthesized in analogy to example 1, from 5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carboxylic acid hydrochloride (example 1, intermediate b), and 1-(piperidin-1-yl-sulfonyl)-piperazine to afford the desired product as a light-brown solid (87%). MS (ISP): 531.2 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07648979B2 |
| Quelldatensatz | uspto-grants-2010_01 |
| ORD ID | ord-4876ddd2906248b899240877ec34e2ae |
| Quellennotiz | uspto-grants-2010_01 |