HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3-Chlorophenyl)boronic acid → [1-(3-Chloro-phenyl)-5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-[4-(piperidine-1-carbonyl)-piperazin-1-yl]-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3-Chlorophenyl)boronic acid | HCID 2734323 | — |
| Edukt | {4-[5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indole-2-carbonyl]-piperazin-1-yl}-piperidin-1-yl-methanone | HCID 68533742 | — |
| Produkt | [1-(3-Chloro-phenyl)-5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-[4-(piperidine-1-carbonyl)-piperazin-1-yl]-methanone | HCID 68536874 | 49% |
Reaktionsschritte
The title compound was synthesized in analogy to example 5, from {4-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carbonyl]-piperazin-1-yl}-piperidin-1-yl-methanone (example 14) and 3-chlorophenylboronic acid to afford the desired product as a light-brown foam (49%). MS (ISP): 605.2 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07648979B2 |
| Quelldatensatz | uspto-grants-2010_01 |
| ORD ID | ord-283f2d610ec44b45a58c9d8632e050f4 |
| Quellennotiz | uspto-grants-2010_01 |