HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(Cyclopropylsulfonyl)piperazine → (4-Cyclopropanesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(Cyclopropylsulfonyl)piperazine | HCID 45496790 | — |
| Edukt | [5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-(4-methanesulfonyl-piperazin-1-yl)-methanone | HCID 68538245 | — |
| Produkt | (4-Cyclopropanesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone | HCID 68535679 | 93% |
Reaktionsschritte
The title compound was synthesized in analogy to example 1, from 5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carboxylic acid hydrochloride (example 1, intermediate b) and cyclopropylsulfonyl-piperazine to afford the desired product as light brown foam (93%). MS (ISP): 488.1 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07648979B2 |
| Quelldatensatz | uspto-grants-2010_01 |
| ORD ID | ord-cfd5e82d764e4117835dfabed1358419 |
| Quellennotiz | uspto-grants-2010_01 |