HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tetrahydro-4H-pyran-4-one → (4-Methanesulfonyl-piperazin-1-yl)-{5-[4-(tetrahydro-pyran-4-yl)-[1,4]diazepane-1-carbonyl]-1H-indol-2-yl}-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tetrahydro-4H-pyran-4-one | HCID 121599 | — |
| Edukt | 4-[2-(4-methanesulfonyl-piperazine-1-carbonyl)-1H-indole-5-carbonyl]-[1,4]diazepane-1-carboxylic acid tert-butyl ester | HCID 68536747 | — |
| Produkt | (4-Methanesulfonyl-piperazin-1-yl)-{5-[4-(tetrahydro-pyran-4-yl)-[1,4]diazepane-1-carbonyl]-1H-indol-2-yl}-methanone | HCID 68534110 | — |
Reaktionsschritte
The title compound was synthesized in analogy to example 47, from 4-[2-(4-methanesulfonyl-piperazine-1-carbonyl)-1H-indole-5-carbonyl]-[1,4]diazepane-1-carboxylic acid tert-butyl ester and tetrahydro-4H-pyran-4-one. Yellow gum. MS (m/z): 518.3 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07648979B2 |
| Quelldatensatz | uspto-grants-2010_01 |
| ORD ID | ord-5ab03cfefd964cbabe49dab22e9a3bb2 |
| Quellennotiz | uspto-grants-2010_01 |