HCID 88662971, Verbindung → HCID 70436618, Verbindung

HRID 1995047Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1995047
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([NH:9][CH:10]1[C:25](=[O:26])[N:12]2[C:13]([C:22]([OH:24])=[O:23])=[C:14](OS(C)(=O)=O)[CH2:15][S:16][C@H:11]12)=[O:8]>C(O)C>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([NH:9][CH:10]1[C:25](=[O:26])[N:12]2[C:13]([C:22]([OH:24])=[O:23])=[CH:14][CH2:15][S:16][C@H:11]12)=[O:8]

Komponenten

3

Edukt 1

HCID 88662971HCID 88662971, Verbindung

Produkt 1

HCID 70436618HCID 70436618, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A 200 mg. portion of 7-(thien-2-ylacetamido)-3-methanesulfonyloxyl-3-cephem-4-carboxylic acid was dissolved in a working fluid containing 2.5 mg./ml. of the starting compound, 35% by volume of ethanol, and 64% by volume of 1.0 molar pH 7.0 McIlvaine buffer. The measured pH of the working fluid was 7.5. The electrolysis was carried out as described in Example 1 in the same type of cell described in Example 1, and the product was worked up as described in Example 2 to obtain about 130 mg. of crude product. The product was converted to the methyl ester, and submitted to mass spectroscopy, which revealed the presence of molecular ions of mass 337 and 338, confirming that the desired product was obtained.

Aufarbeitung

  1. additioncontaining 2.5 mg
  2. customto obtain about 130 mg

Quellen und Nachweise

ORD-Eintrag
ord-2752ce02705b4e3eb6d41414307422b3
Quelldatensatz
uspto-grants-1983_09
Patentnummer
US04402803

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