Potassium Iodide → HCID 20402707, Verbindung

HRID 1995098Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1995098
[C:1]([C:9]1[C:10]([NH:16][C:17](=[O:20])[CH2:18]Cl)=[CH:11][N:12]([CH3:15])[C:13]=1[CH3:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I-:21].[K+]>C(O)C>[C:1]([C:9]1[C:10]([NH:16][C:17](=[O:20])[CH2:18][I:21])=[CH:11][N:12]([CH3:15])[C:13]=1[CH3:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 4875Potassium IodideHCID 20402708HCID 20402708, Verbindung

Produkt 1

HCID 20402707HCID 20402707, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

N-(4-benzoyl-1,5-dimethyl(1H)pyrrol-3-yl)2-chloroacetamide (0.741 mole) and potassium iodide (1.62 mole) were refluxed in ethanol (3400 ml) for 5 hours with stirring. The reaction mixture was then cooled, the inorganic salts were filtered off and the solvent was evaporated under vacuum. The obtained residue was purified by washing first with water and then with cold ethanol. M.p. 135°-137° C. Yield 87%.

Aufarbeitung

  1. temperatureThe reaction mixture was then cooled
  2. filtrationthe inorganic salts were filtered off
  3. customthe solvent was evaporated under vacuum
  4. customThe obtained residue was purified
  5. washby washing first with water

Quellen und Nachweise

ORD-Eintrag
ord-5b0c6240e9054f30a69c9a3fee9ae5b8
Quelldatensatz
uspto-grants-1983_09
Patentnummer
US04402970

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