HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(1,1-dimethylethyl)-N-(phenylmethyl)-4-Piperidinamine → 1-tert-Butylpiperidin-4-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(1,1-dimethylethyl)-N-(phenylmethyl)-4-Piperidinamine | HCID 22647939 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 1-tert-Butylpiperidin-4-amine | HCID 17750401 | 64,7% |
Reaktionsschritte
A solution of N-benzyl-1-tert-butylpiperidin-4-amine (1.56 g) and 10% palladium on carbon (2 g) in MeOH (250 ml) was hydrogenated in a Parr shaker at 50 psi for 16 hours. The solution was filtered and the reaction mixture reduced in vacuo, to yield 1-tert-butylpiperidin-4-amine (0.64 g) (LC/MS: Rt 02.31, no [M+H]+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07745638B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-5abc4cfd8fc54361a1e7c5a7b32fbdbd |
| Quellennotiz | uspto-grants-2010_06 |