Sodium Azide → (3-Azidopropyl)(triphenyl)phosphanium bromide

HRID 2036270Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2036270
[Br-].[Br:2][CH2:3][CH2:4][CH2:5][P+:6]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[N-:25]=[N+:26]=[N-:27].[Na+]>C(O)C.O>[Br-:2].[N:25]([CH2:3][CH2:4][CH2:5][P+:6]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[N+:26]=[N-:27]

Komponenten

4

Edukt 2

HCID 33557Sodium AzideHCID 2723862(3-Bromopropyl)triphenylphosphonium bromide

Produkt 1

HCID 53362697(3-Azidopropyl)(triphenyl)phosphanium bromide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 19096565Water ethanolLösungsmittel

Versuchsvorschrift

(3-Bromo-propyl)-triphenyl-phosphonium bromide was dissolved in ethanol/water (1/1). To it sodium azide was added. The reaction mixture was heated up to reflux overnight. Solvents were removed by evaporation. The residue was extracted by dry ethanol. Filtered and evaporated to give crude (3-azido-propyl)-triphenyl-phosphonium bromide and was used directly for the next step reaction without further purification.

Aufarbeitung

  1. temperatureThe reaction mixture was heated up
  2. temperatureto reflux overnight
  3. customSolvents were removed by evaporation
  4. extractionThe residue was extracted by dry ethanol
  5. filtrationFiltered
  6. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-ad8f3d5f84e949449b76dfa1c4991a85
Quelldatensatz
uspto-grants-2013_11
Patentnummer
US08575176B2

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