Phenylmethyl 3-(4-hydroxybutyl)-1-piperidinecarboxylate → Phenylmethyl 3-(4-bromobutyl)-1-piperidinecarboxylate
Reaktionsgleichung
[Br:1]CCCC1CCCCN1C(OCC1C=CC=CC=1)=O.O[CH2:22][CH2:23][CH2:24][CH2:25][CH:26]1[CH2:31][CH2:30][CH2:29][N:28]([C:32]([O:34][CH2:35][C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)=[O:33])[CH2:27]1>>[Br:1][CH2:22][CH2:23][CH2:24][CH2:25][CH:26]1[CH2:31][CH2:30][CH2:29][N:28]([C:32]([O:34][CH2:35][C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)=[O:33])[CH2:27]1Komponenten
3
Versuchsvorschrift
Prepared similarly to Intermediate 10 from phenylmethyl 3-(4-hydroxybutyl)-1-piperidinecarboxylate (for example, as prepared for Intermediate 23).
Quellen und Nachweise
- ORD-Eintrag
- ord-bb17b09370034ba3986c47d9233c0fe2
- Quelldatensatz
- uspto-grants-2013_11