HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
m-Aminoacetanilide → {2-[3-(3-Acetylamino-phenyl)-3-(3-methyl-butyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | m-Aminoacetanilide | HCID 7604 | — |
| Edukt | 3-Methylbutanal | HCID 11552 | — |
| Edukt | Ethyl 2-(2-aminothiazol-5-ylthio)acetate | HCID 21455623 | — |
| Edukt | {2-[3-Cyclopentylmethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-4-yl}-acetic acid | HCID 57668246 | — |
| Edukt | {2-[3-(3-Acetylamino-phenyl)-3-(3-methyl-butyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester | HCID 86629907 | — |
| Produkt | {2-[3-(3-Acetylamino-phenyl)-3-(3-methyl-butyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid | HCID 57668406 | — |
Reaktionsschritte
The title compound was prepared via {2-[3-(3-acetylamino-phenyl)-3-(3-methyl-butyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using N-(3-amino-phenyl)-acetamide, 3-methylbutanal and (2-amino-thiazol-5-ylsulfanyl)acetic acid ethyl ester.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08586614B2 |
| Quelldatensatz | uspto-grants-2013_11 |
| ORD ID | ord-b1e588bcb93e4d4f98a1813e31594527 |
| Quellennotiz | uspto-grants-2013_11 |