1-Benzyl-3-aminopyrrolidine → HCID 12861944, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[C:3]([N:13]([CH3:15])[CH3:14])=[CH:4][C:5]([O:11][CH3:12])=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[NH2:16][CH:17]1[CH2:21][CH2:20][N:19]([CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH2:18]1>>[CH2:22]([N:19]1[CH2:20][CH2:21][CH:17]([NH:16][C:7](=[O:9])[C:6]2[CH:10]=[C:2]([Cl:1])[C:3]([N:13]([CH3:15])[CH3:14])=[CH:4][C:5]=2[O:11][CH3:12])[CH2:18]1)[C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1Komponenten
3
Versuchsvorschrift
By following general method A using 0.85 g. of 5-chloro-4-dimethylamino-2-methoxybenzoic acid and 0.65 g. of 3-amino-1-benzylpyrrolidine, 0.8 g. of N-(1-benzyl-3-pyrrolidinyl)-5-chloro-4-dimethylamino-2-methoxybenzamide was obtained.
Quellen und Nachweise
- ORD-Eintrag
- ord-394597ba65ba469d8b3f78d2c3ba4c8b
- Quelldatensatz
- uspto-grants-1980_04
- Patentnummer
- US04197243