HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanone, 2-chloro-1,2-diphenyl- → Thiazole, triphenyl-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanone, 2-chloro-1,2-diphenyl- | HCID 95343 | — |
| Edukt | Thiobenzamide | HCID 683563 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | Thiazole, triphenyl- | HCID 1712256 | — |
Reaktionsschritte
Thiobenzamide (13.7 g, 0.10 mole) and desyl chloride (23.1 g, 0.10 mole) are heated under reflux in isopropyl alcohol (100 ml) for three hours. When the reaction mixture is cooled, the white solid precipitate formed is filtered off, washed twice with isopropyl alcohol, and dried. The yield of triphenylthiazole, m.p. 84°-85.5° C., is 21.5 g or 69%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04197306 |
| Quelldatensatz | uspto-grants-1980_04 |
| ORD ID | ord-3912ad2349f94687be5fa180fdf6869a |
| Quellennotiz | uspto-grants-1980_04 |