HCID 14422542, Verbindung → Imidazo[1,5-a]pyridine-3-sulfonamide

HRID 2051131Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2051131
C([NH:5][S:6]([C:9]1[N:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]2=[CH:11][N:10]=1)(=[O:8])=[O:7])(C)(C)C>FC(F)(F)C(O)=O>[CH:11]1[N:10]=[C:9]([S:6]([NH2:5])(=[O:8])=[O:7])[N:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=12

Komponenten

3

Edukt 1

HCID 14422542HCID 14422542, Verbindung

Produkt 1

HCID 19832737Imidazo[1,5-a]pyridine-3-sulfonamideAusbeute 77,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6422Trifluoroacetic acidLösungsmittel

Versuchsvorschrift

N-(t-Butyl)imidazo[1,5-a]pyridine-3-sulfonamide (1.0 g) is dissolved in 20 ml of trifluoroacetic acid and stirred for 14 days at room temperature. The mixture is concentrated under reduced pressure, and ether is added to the residue to precipitate crystals. The crystals are collected by filtration and dried to give 0.60 g of the title compound. mp. 179°-180° C.

Aufarbeitung

  1. concentrationThe mixture is concentrated under reduced pressure, and ether
  2. additionis added to the residue
  3. customto precipitate crystals
  4. filtrationThe crystals are collected by filtration
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-93a5aa6cf675491eb5055d96c4015b00
Quelldatensatz
uspto-grants-1991_05
Patentnummer
US05017212

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