HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 4-{[3-(4-Chlorophenyl)propyl]amino}benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Ethanol | HCID 702 | — |
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | Ethyl 4-{[3-(4-chlorophenyl)propyl]amino}benzoate | HCID 13079692 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 4-{[3-(4-Chlorophenyl)propyl]amino}benzoic acid | HCID 13079691 | — |
Reaktionsschritte
A mixture of 16.3 g. of ethyl 4-[3-(p-chlorophenyl)propylamino]benzoate, 16.3 g. of potassium hydroxide and 200 ml. of 95% ethanol is refluxed for 3 hours. The mixture is diluted with 100 ml. of water brought to pH 6 with concentrated hydrochloric acid. Chilling and filtering gave 15 g. of white crystals. Recrystallization from ethanol gave 8.6 g. of white crystals, m.p. 191°-192° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04185115 |
| Quelldatensatz | uspto-grants-1980_01 |
| ORD ID | ord-827cf6daf3cb43fdb27a1921f706f6e7 |
| Quellennotiz | uspto-grants-1980_01 |