HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methanol → Methyl-7-methylsulfamoyl-1,4-benzodioxane-5-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methanol | HCID 887 | — |
| Edukt | Sulfuric Acid | HCID 1118 | — |
| Edukt | Sodium Carbonate | HCID 10340 | — |
| Edukt | 2,3-Dihydro-7-(N-methylsulphamoyl)-1,4-benzodioxin-5-carboxylic acid | HCID 6455317 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Methyl-7-methylsulfamoyl-1,4-benzodioxane-5-carboxylate | HCID 54343297 | 85% |
Reaktionsschritte
750 ml of methanol were introduced into a balloon flask provided with a condenser. Then, under cooling, 273 g of concentrated sulfuric acid and 160 g of 7-methylsulfamoyl-1,4-benzodioxane-5-carboxylic acid were added. The mixture was heated under reflux, cooled and poured into water and sodium carbonate. The precipitate was dried off, washed and dried. 143 g of methyl-7-methylsulfamoyl-1,4-benzodioxane-5-carboxylate were obtained (M.P.: 159°-160° C.; yield: 85%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04186135 |
| Quelldatensatz | uspto-grants-1980_01 |
| ORD ID | ord-cf47865242764896a3d20ceb75533f2e |
| Quellennotiz | uspto-grants-1980_01 |