HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl 2-(3-aminophenoxy)acetate → (3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl 2-(3-aminophenoxy)acetate | HCID 412308 | — |
| Edukt | 5-(3-Chlorophenyl)furan-2-carboxylic acid | HCID 736256 | — |
| Produkt | (3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester | HCID 59654640 | — |
Reaktionsschritte
Carboxylic acid (65) (67 mg, 0.3 mmol) was coupled to ethyl ester (64) (58 mg, 0.25 mmol) using Method C. The crude residue was purified by column chromatography eluting with a stepped gradient of 10-20% EtOAc in heptane to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07326732B2 |
| Quelldatensatz | uspto-grants-2008_02 |
| ORD ID | ord-985823996b574632bbff8b33009b3daf |
| Quellennotiz | uspto-grants-2008_02 |