HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(3-Chlorophenyl)furan-2-carboxylic acid → 5-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-1H-indole-2-carboxylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-(3-Chlorophenyl)furan-2-carboxylic acid | HCID 736256 | — |
| Edukt | Ethyl 5-amino-1H-indole-2-carboxylate | HCID 10726872 | — |
| Produkt | 5-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-1H-indole-2-carboxylic acid ethyl ester | HCID 59654633 | — |
Reaktionsschritte
5-(3-Chloro-phenyl)-furan-2-carboxylic acid (65) (54 mg, 0.24 mmol) was coupled to ethyl ester (58) (50 mg, 0.24 mmol) using Method C. The crude residue was purified by column chromatography eluting with 20% EtOAc in heptane to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07326732B2 |
| Quelldatensatz | uspto-grants-2008_02 |
| ORD ID | ord-a4a0c2e2cc1b4c928b3665909ce4d6e5 |
| Quellennotiz | uspto-grants-2008_02 |